The Seemann Environmental Toxicology Lab

Characterization of immune aging in the Japanese Medaka (Oryzias latipes) 

DiBona, E., Humble, J.L., Duran, D., Au, D.W.T., Seemann, F. 2024. Fishes 9(9), 333. 

Analysis of the Skin and Brain Transcriptome of Normally Pigmented and Psuedo-Albino Southern Flounder (Paralichthys lethostigma) Juveniles to Study the Molecular Mechanisms of Hypopigmentation and Its Implication for Species Survival in the Natural Environment

Blandon, I., DiBona, E., Battenhouse, A., Vargas, S., Mace, C., Seemann, F. 2024. Int J Mol Sci 25(14), 7775. 

The role of DNA methylation on gene expression in vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka

Wan, T., Mo, J., Au, D. W.-T., Qin, X., Tam, N. Y.-K., Kong, R. Y.-C., Seemann, F. 2023. Epigenetics 18(1), 2222246. (IF 4.89) 

Multigenerational impacts of EE2 on reproductive fitness and immune competence of marine medaka

Peterson, D. R., Seemann, F., Wan, T., Ye, R. R., Chen, L., Lai, K. P., Yu, P., Kong, R. Y. C., Au, D. W. T. 2023. Aquatic toxicology 260: 106584. (IF 4.70)

Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a] pyrene exposure: cellular and transcriptomic insights

Mo, J., Wan, M.T., Au, D.W.T., Shi, J., Tam, N., Qin, X., Cheung, N.K., Lai, K.P., Winkler, C., Kong, R.Y.C., Seemann, F. 2023. Journal of Environmental Sciences. (IF 6.40)

Using visualization techniques to assess the accumulation of nanoplastics with varying surface modifications

Simpson, K., Armijo, L., Fritz, S., DiBona, E., Seemann, F., Sheng, J., Xu, W. 2023. SPIE. (IF 0.38)

Developmental polyethylene microplastic fiber exposure entails subtle reproductive impacts in juvenile Japanese Medaka (Oryzias latipes)

DiBona, E., Haley, C., Geist, S., Seemann, F. 2022. Environmental Toxicology and Chemistry. (IF 3.41) 

Assessment of parental benzo[a]pyrene exposure-induced cross-generational neurotoxicity and changes in offspring sperm DNA methylome in medaka fish

Wan, T., Au, D.W.T., Mo, J., Chen, L., Cheung, K.M., Kong, R.Y.C. and Seemann, F. 2022. Environmental Epigenetics 8(1). (IF 3.42)

A holistic assessment of polyethylene fiber ingestion in larval and juvenile Japanese medaka fish

DiBona E., Pinnel, L.J., Heising-Huang, A., Geist, S., Tuner, J.W., Seemann, F. 2021. Frontiers in Physiology: Aquatic Physiology (IF 4.56)

Benzo[a]pyrene osteotoxicity and the regulatory roles of genetic and epigenetic factors: a review

Mo J., Au D.W.T., Guo J., Winkler C., Kong R.C-Y., Seemann F. 2021. Critical Reviews in Environmental Science and Technology (IF 12.56)

Multigenerational impacts of benzo[a]pyrene on bone modeling and remodeling in medaka (Oryzias latipes)

Mo J.Z., Au D.W.T., Wan, M.T., Shi J.C., Zhang G., Winkler C.W., Kong R.Y.C, Seemann F. 2020. Environmental Science & Technology (IF 7.86)

Sex-specific immunomodulatory action of the environmental estrogen 17α-ethynylestradiol alongside with reproductive impairment in fish

Ye R.R., Peterson, D.R., Kitamura, S., Segner, H., Seemann F., Au, D.W.T. 2018. Aquatic Toxicology 203, 95-106. (IF 4.14)

Modification of the plasma complement protein profile by exogenous estrogens is indicative of a compromised immune competence in marine medaka (Oryzias maleastigma)

Dong M., Seemann F., Humble J.L., Liang Y., Peterson D.R., Ye R.R., Ren H., Kim H., Lee J.-S., Au, D.W.T., Yun W.L. 2017. Fish & Shellfish Immunology 70, 260-269. (IF 3.15)

 The development of cellular immune defence in marine medaka Oryzias melastigma

Seemann F., Peterson D.R., Chiang M.W.L., Au D.W.T. 2017. Comparative Biochemistry and Physiology, Part C, 19, 81-89. (IF 2.42)

Ancestral benzo(a)pyrene exposure affects bone integrity and deregulates osteogenic miRNA expression in adult F3 fish (Oryzias latipes)

Seemann F., Jeong C.-B., Zhang G., Wan M.T., Guo B.-S., Peterson D.R., Lee J.-S., Au D.W.T. 2017. Aquatic Toxicology 183, 127-134 (IF 4.13)

Immune competence assessment in marine medaka (Oryzias melastigma) – a holistic approach for immunotoxicology

Ye R.R., Peterson D.R., Seemann F., Kitamura S.-I., Lee J.-S., Lau T.C.K., Tsui S.K.W., Au D.W.T. 2016. Environmental Science and Pollution Research, 1-15 (epub) (IF 2.74)

Chronic exposure of marine medaka (Oryzias melastigma) to 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) reveals its mechanism of action in endocrine disruption via the hypothalamus-pituitary-gonadal-liver (HPG) axis

Chen L.G., Zhang W.P., Ye R.R., Hu C.Y, Wang Q.W., Seemann F., Au D.W.T., Zhou B., Giesy J.P., Qian P.-Y. 2016. Environmental Science and Technology 50(8), 4492-4501 (IF 6.20)

Insight into the transgenerational effect of benzo(a)pyrene on bone formation in a teleost fish (O. latipes)

Seemann F., Peterson D.R., Witten P.E., Guo B.-S., Shanthanagouda A.H., Ye R.R., Zhang G., Au D.W.T. 2015. Comparative Biochemistry and Physiology, Part C 178, 60-67. (IF 2.55)

Sensitive periods for 17β-estradiol exposure during immune system development in sea bass head kidney

Seemann F., Knigge T., Duflot A., Marie S., Olivier S., Minier C., Monsinjon T. 2015. Journal of Applied Toxicology 36(6), 815-826. (IF 2.72)

Exogenous 17β-estradiol modifies thymus growth and regionalization in European sea bass Dicentrarchus labrax

Seemann F., Knigge T., Olivier S., Monsinjon T. 2015. Journal of Fish Biology 86, 1186-1198. (IF 1.25)

17β-estradiol exposure changes levels in blood and head kidney of juvenile sea bass (Dicentrarchus labrax, L., 1758)

Seemann F., Knigge T., Rocher B., Minier C., Monsinjon T. 2013. Marine Environmental Research 87-88, 44-51. (IF 2.77(